Rance Roden plans to kill off all the buffalo and thus cause the Indians to riot. After the Indians destroy the US Cavalry, Rance and his gang plan to take over the West. Meanwhile, a Boston magazine gets wind of the buffalo slaughter and sends Ken Cabot and his Stooge associates to Casper, WY to investigate. Once there, Ken's shooting skill, secretly aided by Annie Oakley, earns him the title of Sheriff. Rance calls on his band of outlaws to have them all killed, but Moe, Larry and Curly Joe sneak into the gang's hideout while they are asleep and glue their firearms to their holsters. When Ken confronts the bad guys and wins, the bad guys (with Stooge-like prompting from the boys) decide that a life of justice is better than crime. Meanwhile, Rance and Trigger attempt to sell firearms and a war wagon to the Indians, and the Stooges attempt to foil this plan by snapping a picture of them in the process. 1965