The sci-fi actioner is set 400 years in the future, when disease has wiped out the majority of the earth's population except for one walled, protected city-state, Bregna, ruled by a congress of scientists. The story centers on Aeon Flux(Theron), the top operative in the underground 'Monican' rebellion, led by The Handler(Frances McDormand). When Aeon is sent on a mission to kill a government leader, she uncovers a world of secrets...