Breaking the cardinal rules of spin-the-bottle, 10 year old Charlie Logan refused to lip-lock with a demented Goth girl – and she put a hex on him. Now, twenty-five years later, Charlie (Dane Cook) is a successful dentist…and still cursed, discovering that every woman he’s ever slept with has found true love – with the next guy after him. But when a genuine romance develops with an accident prone penguin specialist (Jessica Alba), Charlie realizes he’s got to find a way to break his good-luck curse…before the girl of his dreams winds up with the next guy she meets.