Star Wars: Republic Commando follows the tale of 'Delta Squad', an elite group of clone commandos, through three missions during the Clone Wars. Trained in squads of four by Mandalorian mercenaries such as Walon Vau and Kal Skirata, the commandos were more capable than their rank-and-file clone brethren, having undergone live-fire training as opposed to mere computerized simulations. All clone commandos were proficient with a large variety of weapons, computer systems, and demolitions equipment.
The game covers Delta Squad’s activities in three locations, the planet Geonosis, a derelict Acclamator I-class assault ship designated the Prosecutor, and the planet Kashyyyk. In each location, the player leads the squad through a series of objectives while battling against enemy forces ranging from droids to Trandoshans. The player is assisted throughout the game by a clone advisor designated CC-01/425 who updates mission objectives as each level progresses.