Family Chat: Circumcise or NotThe foreskin has protective, sensory, biomechanical, and immunological functions. Throughout life, the outer part of the foreskin protects the sensitive inner part of the foreskin and the glans from injury, abrasion, chafing, and infection. The foreskin keeps its mucosal tissue and the glans soft and moist so that it maintains sensitivity. During sexual activity, the foreskin glides up and down over the glans, providing sensation from thousands of specialized nerve endings in the inner foreskin. Parts of the foreskin, including the frenulum (a narrow membrane on the underside of the foreskin) and the ridged band (the edge of the foreskin, between the inner and outer skin), are particularly important in sexual function. See the Circumcision Information Resource Center, under "Foreskin sexual function." Circumcision removes most of the inner and outer foreskin, and destroys these functions. The foreskin secretes immunological substances that fight infection, called lysozymes, and also produces natural lubricants, reducing the need for artificial lubricants during sex. The presence of the foreskin can enhance the sexual experience for both partners. Polls of women who had experienced both circumcised and uncircumcised partners indicated a strong preference for the latter, with longer duration of coitus and higher rate of orgasm cited as the main reasons (for example, see "The effect of male circumcision on the sexual enjoyment of the female partner").